2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor mAChR Adrenergic Receptor 5-HT Receptor
  4. Clozapine (Standard)

Clozapine (Standard)  (Synonyms: HF 1854 (Standard))

Cat. No.: HY-14539R Purity: 99.98%
SDS COA Handling Instructions Technical Support

Clozapine (Standard) is the analytical standard of Clozapine. This product is intended for research and analytical applications. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM).

For research use only. We do not sell to patients.

Clozapine (Standard) Chemical Structure

Clozapine (Standard) Chemical Structure

CAS No. : 5786-21-0

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Clozapine (Standard) Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clozapine (Standard)5786-21-0HF 1854 (Standard)Dopamine ReceptormAChRAdrenergic Receptor5-HT ReceptorMuscarinic acetylcholine receptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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