1. Neuronal Signaling
  2. Sigma Receptor
  3. CM764

CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD+/NADH, and ATP levels, and decreases the concentration of ROS.

For research use only. We do not sell to patients.

CM764 Chemical Structure

CM764 Chemical Structure

CAS No. : 1350296-29-5

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Description

CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD+/NADH, and ATP levels, and decreases the concentration of ROS[1].

IC50 & Target

Sigma 2 Receptor

3.5 nM (Ki)

Sigma 1 Receptor

86.6 nM (Ki)

Molecular Weight

426.48

Formula

C23H27FN4O3

CAS No.
SMILES

O=C1OC2=CC(C(C)=O)=CC=C2N1CCCCN3CCN(C4=CC=C(F)C=C4N)CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CM764
Cat. No.:
HY-117420
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