1. Anti-infection NF-κB
  2. Bacterial NF-κB
  3. Colistin adjuvant-1

Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM.

For research use only. We do not sell to patients.

Colistin adjuvant-1 Chemical Structure

Colistin adjuvant-1 Chemical Structure

CAS No. : 2862800-15-3

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Description

Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM[1].

In Vitro

Colistin adjuvant-1 (compound 13) inhibits a panel of additional colistin-resistant strains of K. pneumoniae and A. baumannii, including strains harboring the mcr-1 gene, and also determined activity against colistin-resistant strains of P. aeruginosa[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

414.23

Formula

C16H7F9N2O

CAS No.
SMILES

OC(C=C(C(F)(F)F)C=C1)=C1C2=NC3=C(C(F)(F)F)C=C(C(F)(F)F)C=C3N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Colistin adjuvant-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Colistin adjuvant-1
Cat. No.:
HY-145439
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