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  4. Concanavalin A

Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury.

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Concanavalin A Chemical Structure

Concanavalin A Chemical Structure

CAS No. : 11028-71-0

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Based on 2 publication(s) in Google Scholar

Concanavalin A Related Antibodies

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Description

Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury[1][3].

In Vivo

Concanavalin A (20 mg/kg; i.v.) induces autoimmune hepatitis in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks, 20 g Male Balb/c mice[3]
Dosage: 20 mg/kg
Administration: I.v.
Result: Increased the ALT and AST levels after 8 hours.
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[Concanavalin A]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (Need ultrasonic)

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Purity & Documentation

SDS (418 KB)

COA (243 KB)

Handling Instructions (2659 KB)
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Concanavalin A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Concanavalin A11028-71-0AntibioticApoptosismannoseglucoseplant lectinjack beanprogrammed cell deathInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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