Conessine dihydrobromide

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Conessine dihydrobromide is a steroidal alkaloid and an effective, selective histamine H3 receptor antagonist with K_i values of 5.4, 6.0, 5.7, and 25 nM for human, dog, guinea pig, and rat H3 receptors, respectively. Conessine dihydrobromide exhibits antimalarial activity and can be used in infection-related research.

For research use only. We do not sell to patients.

Conessine dihydrobromide Chemical Structure

CAS No. : 5913-82-6

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Other Forms of Conessine dihydrobromide:

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Description	Conessine dihydrobromide is a steroidal alkaloid and an effective, selective histamine H3 receptor antagonist with K_i values of 5.4, 6.0, 5.7, and 25 nM for human, dog, guinea pig, and rat H3 receptors, respectively. Conessine dihydrobromide exhibits antimalarial activity and can be used in infection-related research^[1]^[2].
Molecular Weight	518.41
Formula	C₂₄H₄₂Br₂N₂
CAS No.	5913-82-6
SMILES	C[C@H]1[C@]2([H])[C@]3(CN1C)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)N(C)C)=CC4)C)([H])CC3.Br.Br
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Santora VJ, et al. A new family of H3 receptor antagonists based on the natural product Conessine. Bioorg Med Chem Lett. 2008;18(4):1490-1494 [Content Brief] [2]. Kim H, et al. Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression [published online ahead of print, 2018 Feb 1]. J Microbiol Biotechnol. 2018;10.4014.jmb.1711.11009 [Content Brief]