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  3. Coronalolic acid

Coronalolic acid  (Synonyms: Coronalonic acid)

Cat. No.: HY-N3625
Handling Instructions

Coronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production.

For research use only. We do not sell to patients.

Coronalolic acid Chemical Structure

Coronalolic acid Chemical Structure

CAS No. : 268214-52-4

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Description

Coronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production[1].

IC50 & Target[1]

NF-κB

 

In Vitro

Coronalolic acid has an inhibition effect against the TNF-α-induced NF-κB activity and NO production with IC50s of 15.4 μM and 15.0 μM in LPS-stimulated RAW 264.7 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

470.68

Formula

C30H46O4

CAS No.
SMILES

OC(CC[C@@]12[C@]3([C@](CC[C@H]2C(CO)=C)([H])[C@]4([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC4)CC3)C)C1)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Coronalolic acid
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