2. Natural Products
  3. Disease Research Fields Plants Terpenoids
  4. Zingiberaceae Other Diseases Diterpenoids
  5. Hedychium coronarium Koen.
  6. Coronarin D

Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium.

For research use only. We do not sell to patients.

Coronarin D Chemical Structure

Coronarin D Chemical Structure

CAS No. : 119188-37-3

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Based on 1 publication(s) in Google Scholar

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Description

Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium[1].

Cellular Effect
Cell Line Type Value Description References
A549 GI50
8 μM
Compound: 3
Growth inhibition of human A549 cells by Sulforhodamine B assay
Growth inhibition of human A549 cells by Sulforhodamine B assay
[PMID: 21106458]
BMDC IC50
41.72 μM
Compound: 4
Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA
Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA
[PMID: 22071304]
HeLa GI50
47 μM
Compound: 3
Growth inhibition of human HeLa cells by Sulforhodamine B assay
Growth inhibition of human HeLa cells by Sulforhodamine B assay
[PMID: 21106458]
MCF7 GI50
17.4 μM
Compound: 3
Growth inhibition of human MCF7 cells by Sulforhodamine B assay
Growth inhibition of human MCF7 cells by Sulforhodamine B assay
[PMID: 21106458]
SK-N-SH GI50
20.1 μM
Compound: 3
Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay
Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay
[PMID: 21106458]
Molecular Weight

318.45

Formula

C20H30O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1(C2C/C=C3C(OC(O)C\3)=O)C(CCC2=C)C(C)(CCC1)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥97.0%

SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References
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Coronarin D Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Coronarin D119188-37-3Otherscytotoxiclabdan-type diterpenesrhizomesH. coronariumInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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