2. Immunology/Inflammation
  3. COX
  4. COX-2-IN-28

COX-2-IN-28 is a potent and selective COX-2 inhibitor with IC50 values of 0.054, 2.14, 13.21 µM for COX-2, 15-LOX, COX-1,respectively.

For research use only. We do not sell to patients.

COX-2-IN-28 Chemical Structure

COX-2-IN-28 Chemical Structure

CAS No. : 2413565-18-9

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COX-2-IN-28 Related Antibodies

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Description

COX-2-IN-28 is a potent and selective COX-2 inhibitor with IC50 values of 0.054, 2.14, 13.21 µM for COX-2, 15-LOX, COX-1,respectively[1].

IC50 & Target[1]

COX-1

13.21 μM (IC50)

COX-2

0.054 μM (IC50)

15-LOX

2.14 μM (IC50)

In Vitro

COX-2-IN-28 (compound 15c) shows significant COX-2 selectivity with an SI value of 244.63[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

COX-2-IN-28 Related Antibodies
Molecular Weight

581.78

Formula

C30H27N7S3
CAS No.
SMILES

C/C(CNC1=NC(N2C(SC)=NC3=CC=CC=C23)=CS1)=N\N=C4SC=C(C5=CC=C(C)C=C5)N/4C6=CC=CC=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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COX-2-IN-28 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-2-IN-282413565-18-9COXCyclooxygenaseanti-inflammatorybenzimidazole-thiazole hybridsInhibitorinhibitorinhibit

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