2. Immunology/Inflammation
  3. COX
  4. COX-2-IN-52

COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. COX-2-IN-52 can inhibit the release of NO in cells and has anti-inflammatory activity. COX-2-IN-52 has high gastrointestinal safety and can be used in the research of oral anti-inflammatory drugs.

For research use only. We do not sell to patients.

COX-2-IN-52 Chemical Structure

COX-2-IN-52 Chemical Structure

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COX-2-IN-52 Related Antibodies

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Description

COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. COX-2-IN-52 can inhibit the release of NO in cells and has anti-inflammatory activity. COX-2-IN-52 has high gastrointestinal safety and can be used in the research of oral anti-inflammatory drugs[1].

IC50 & Target[1]

COX-2

54 nM (IC50)

COX-1

15.98 μM (IC50)

Molecular Weight

516.33

Formula

C16H13IN4O4S2
SMILES

O=C(O)CSC1=NN=C(C2=CC=C(S(=O)(N)=O)C=C2)N1C3=CC=C(I)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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COX-2-IN-52 Related Classifications

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Keywords:

COX-2-IN-52COXCyclooxygenaseRAW 246.7Inhibitorinhibitorinhibit

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HY-168888
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