2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. CP-135807

CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research.

For research use only. We do not sell to patients.

CP-135807 Chemical Structure

CP-135807 Chemical Structure

CAS No. : 151272-90-1

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Based on 1 publication(s) in Google Scholar

CP-135807 Related Antibodies

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Description

CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research[1][2].

IC50 & Target[1][2]

5-HT1D Receptor

3.1 nM (IC50, rat)

5-HT1D Receptor

33 nM (IC50, bovine)

In Vivo

Pigeons were trained to peck a key under a multiple fixed-ratio 25 fixed-ratio 175 schedule of food presentation. CP-135807 (0.1 mg/kg; i.m.; single dose) fully and dose-dependently substitutes for the training dose in adult male Carneau pigeons[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

351.40

Formula

C19H21N5O2
CAS No.
SMILES

O=[N+](C1=CC=CN=C1NC2=CC3=C(NC=C3C[C@@H]4N(C)CCC4)C=C2)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CP-135807 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CP-135807151272-90-1CP135807CP 1358075-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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