Croconic acid disodium (Synonyms: Nacr)

Cat. No.: HY-W105310A Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Croconic acid (disodium) (Nacr) can promote cell growth and proliferation by enhancing the expression of genes associated with lysine crotonylation (Kcr) modification. Croconic acid holds potential for improving somatic cell nuclear transfer (SCNT) efficiency and optimizing cell culture conditions research

For research use only. We do not sell to patients.

Croconic acid disodium Chemical Structure

CAS No. : 14379-00-1

Size	Stock	Quantity
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Description

Molecular Weight

186.03

Formula

C₅Na₂O₅

CAS No.

14379-00-1

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C(C(O[Na])=C(C1=O)O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (268.77 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3755 mL	26.8774 mL	53.7548 mL
5 mM	1.0751 mL	5.3755 mL	10.7510 mL
10 mM	0.5375 mL	2.6877 mL	5.3755 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (257 KB) CNMR (169 KB)

Handling Instructions (2659 KB)

References

[1]. Zhao X, et al. High histone crotonylation modification in bovine fibroblasts promotes cell proliferation and the developmental efficiency of preimplantation nuclear transfer embryos. Sci Rep. 2024 May 4;14(1):10295. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.3755 mL	26.8774 mL	53.7548 mL	134.3869 mL
	5 mM	1.0751 mL	5.3755 mL	10.7510 mL	26.8774 mL
	10 mM	0.5375 mL	2.6877 mL	5.3755 mL	13.4387 mL
	15 mM	0.3584 mL	1.7918 mL	3.5837 mL	8.9591 mL
	20 mM	0.2688 mL	1.3439 mL	2.6877 mL	6.7193 mL
	25 mM	0.2150 mL	1.0751 mL	2.1502 mL	5.3755 mL
	30 mM	0.1792 mL	0.8959 mL	1.7918 mL	4.4796 mL
	40 mM	0.1344 mL	0.6719 mL	1.3439 mL	3.3597 mL
	50 mM	0.1075 mL	0.5375 mL	1.0751 mL	2.6877 mL
	60 mM	0.0896 mL	0.4480 mL	0.8959 mL	2.2398 mL
	80 mM	0.0672 mL	0.3360 mL	0.6719 mL	1.6798 mL
	100 mM	0.0538 mL	0.2688 mL	0.5375 mL	1.3439 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Croconic acid disodium Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Croconic acid disodium14379-00-1NacrBiochemical Assay ReagentsCell growthCell proliferationInhibitorinhibitorinhibit

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Croconic acid disodium (Synonyms: Nacr)

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