2. PROTAC
  3. PROTACs
  4. CST967

CST967 (Compound 17) is a USP7 PROTAC degrader, and increasing the PROTAC concentration can enhance the degradation rate of USP7. CST967 can be used in cancer research.

For research use only. We do not sell to patients.

CST967 Chemical Structure

CST967 Chemical Structure

Size Price Stock Quantity
1 mg USD 740 In-stock
5 mg USD 1850 In-stock
10 mg USD 2500 In-stock
25 mg USD 4423 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

CST967 Related Antibodies

Top Publications Citing Use of Products

View All PROTACs Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

CST967 (Compound 17) is a USP7 PROTAC degrader, and increasing the PROTAC concentration can enhance the degradation rate of USP7. CST967 can be used in cancer research[1].

Molecular Weight

927.05

Formula

C51H58N8O9
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N(C1CCC(NC1=O)=O)C2=O)C(C2=C3)=CC=C3N4CCC(C(N5CCC(CCC(NC6=CC=C7C(N=CN(CC8(O)CCN(C(C[C@@H](C)C9=CC=CC=C9)=O)CC8)C7=O)=C6)=O)CC5)=O)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (107.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0787 mL 5.3935 mL 10.7869 mL
5 mM 0.2157 mL 1.0787 mL 2.1574 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0787 mL 5.3935 mL 10.7869 mL 26.9673 mL
5 mM 0.2157 mL 1.0787 mL 2.1574 mL 5.3935 mL
10 mM 0.1079 mL 0.5393 mL 1.0787 mL 2.6967 mL
15 mM 0.0719 mL 0.3596 mL 0.7191 mL 1.7978 mL
20 mM 0.0539 mL 0.2697 mL 0.5393 mL 1.3484 mL
25 mM 0.0431 mL 0.2157 mL 0.4315 mL 1.0787 mL
30 mM 0.0360 mL 0.1798 mL 0.3596 mL 0.8989 mL
40 mM 0.0270 mL 0.1348 mL 0.2697 mL 0.6742 mL
50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.5393 mL
60 mM 0.0180 mL 0.0899 mL 0.1798 mL 0.4495 mL
80 mM 0.0135 mL 0.0674 mL 0.1348 mL 0.3371 mL
100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2697 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

CST967 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CST967CST 967CST-967PROTACsMM.1SCancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
CST967
Cat. No.:
HY-160502
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.