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  5. Cudratricusxanthone A

Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes.

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Cudratricusxanthone A Chemical Structure

Cudratricusxanthone A Chemical Structure

CAS No. : 740810-42-8

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Description

Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
5.93 μM
Compound: 1
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
[PMID: 15787460]
SK-OV-3 IC50
7.09 μM
Compound: 1
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
[PMID: 15787460]
Molecular Weight

396.43

Formula

C23H24O6

CAS No.
SMILES

O=C1C2=C(OC3=C1C(O)=CC(O)=C3C(C)(C)C=C)C=C(O)C(O)=C2C/C=C(C)\C

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cudratricusxanthone A
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