Cupressuflavone

Name: Cupressuflavone
Brand: MedChemExpress
SKU: HY-N9173
Rating: 4.5 (1 reviews)

Cat. No.: HY-N9173: Data Sheet
SDS

COA
Handling Instructions Technical Support

Cupressuflavone is a natural product that can be found in Cupressus macrocarpa. Cupressuflavone exhibits anti-inflammatory and antiulcerogenic activities. Cupressuflavone also show protective effects against CCl₄-induced hepato- and nephrotoxicity in mice.

For research use only. We do not sell to patients.

Cupressuflavone Chemical Structure

CAS No. : 3952-18-9

Size	Price	Stock	Quantity
1 mg	USD 430	In-stock	Estimated Time of Arrival: April 4
5 mg	USD 1300	In-stock	Estimated Time of Arrival: April 4
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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
HT-29	IC₅₀	≥ 50 μM Compound: Cupressuflavone	Antiproliferative activity against human HT-29 cells assessed as decrease in cell viability after 24 hrs by CCK8 assay Antiproliferative activity against human HT-29 cells assessed as decrease in cell viability after 24 hrs by CCK8 assay	[PMID: 30108705]

In Vitro

Cupressuflavone (40-160 mg/kg; p.o. once daily for 5 days) exerts a beneficial effect against oxidative stress by enhancing the antioxidant defense status, reducing lipid peroxidation, and protecting against the pathological changes induced by CCl₄ in the liver and kidney tissues^[1].
Cupressuflavone (40-160 mg/kg; p.o.) inhibits paw edema by 55, 60, and 64% at the three doses of 40, 100, and 160 mg/kg, respectively in the carrageenan-induced paw edema model of inflammation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

538.46

Formula

C₃₀H₁₈O₁₀

CAS No.

3952-18-9

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C4=C5C(C(C=C(C6=CC=C(O)C=C6)O5)=O)=C(O)C=C4O)C(O)=CC(O)=C13

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 99.32%

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Data Sheet (269 KB) SDS (252 KB)

COA (251 KB) HNMR (171 KB) CNMR (189 KB) RP-HPLC (355 KB) MS (461 KB)

Handling Instructions (2659 KB)

References

[1]. Al-Sayed E, et, al. Protective role of Cupressuflavone from Cupressus macrocarpa against carbon tetrachloride-induced hepato- and nephrotoxicity in mice. Planta Med. 2014 Dec;80(18):1665-71. [Content Brief]

[2]. Al-Sayed E, et, al. Anti-inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro-inflammatory mediators. Drug Dev Res. 2018 Feb;79(1):22-28. [Content Brief]

[3]. Koriem KMM, et, al. Protective effect of Cupressus sempervirens extract against indomethacin-induced gastric ulcer in rats. Interdiscip Toxicol. 2015 Mar;8(1):25-34. [Content Brief]