Curculigoside C 

Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively^[1].

Curculigoside C displays neuroprotective effect in the evaluation of salvaging SY5Y cell death induced by H₂O₂^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Curculigoside C (15, 30 and 60 mg/kg) exhibits rapid oral absorption (T_max = 0.106 h, 0.111 h, and 0.111 h, respectively), high elimination (t_1/2 = 2.022 h, 2.061 h, and 2.048 h, respectively) and low absolute bioavailability (2.01%, 2.13%, and 2.39%, respectively)^[2].
Pharmacokinetic parameters of CC in rat plasma after intragastric administration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

482.43

C₂₂H₂₆O₁₂

851713-74-1

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C=CC(O)=C2)=C2COC(C3=C(C(O)=CC=C3OC)OC)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wu Q, et al. Antioxidative phenols and phenolic glycosides from Curculigo orchioides. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1065-7.  [Content Brief]

  [2]. Di Wu, et al. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS. Molecules. 2018 Dec 21;24(1):21.  [Content Brief]