2. GPCR/G Protein
  3. Adenosine Receptor
  4. CVT-5440

CVT-5440 is a xanthine based, selective, high affinity A2B adenosine receptors (AdoR) antagonist with a Ki of 50 nM (selectivity A1> 200; A2A>200; A3>167). CVT-5440 has the potential for asthma research.

For research use only. We do not sell to patients.

CVT-5440 Chemical Structure

CVT-5440 Chemical Structure

CAS No. : 531506-64-6

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CVT-5440 Related Antibodies

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Description

CVT-5440 is a xanthine based, selective, high affinity A2B adenosine receptors (AdoR) antagonist with a Ki of 50 nM (selectivity A1> 200; A2A>200; A3>167). CVT-5440 has the potential for asthma research[1].

IC50 & Target[1]

A2B

50 nM (Ki)

A1

>10,000 nM (Ki)

A2A

>5,000 nM (Ki)

Molecular Weight

516.55

Formula

C27H28N6O5
CAS No.
SMILES

O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=C(OCC4=NOC(C5=CC=CC(OC)=C5)=N4)C=C3)N2)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CVT-5440 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CVT-5440531506-64-6CVT5440CVT 5440Adenosine ReceptorP1 receptorXanthineasthmaInhibitorinhibitorinhibit

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