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  2. Fluorescent Dye
  3. Cy5-PEG3-endo-BCN

Cy5-PEG3-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

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Cy5-PEG3-endo-BCN Chemical Structure

Cy5-PEG3-endo-BCN Chemical Structure

CAS No. : 1881221-50-6

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Description

Cy5-PEG3-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

Molecular Weight

869.57

Formula

C51H69ClN4O6

CAS No.
Appearance

Solid

Color

Purple to purplish red

SMILES

CC1(C)C2=CC=CC=C2[N+](CCCCCC(NCCOCCOCCOCCNC(OC[C@H]3[C@]4([H])[C@@]3([H])CCC#CCC4)=O)=O)=C1/C=C/C=C/C=C5N(C6=CC=CC=C6C\5(C)C)C.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (57.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1500 mL 5.7500 mL 11.4999 mL
5 mM 0.2300 mL 1.1500 mL 2.3000 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1500 mL 5.7500 mL 11.4999 mL 28.7498 mL
5 mM 0.2300 mL 1.1500 mL 2.3000 mL 5.7500 mL
10 mM 0.1150 mL 0.5750 mL 1.1500 mL 2.8750 mL
15 mM 0.0767 mL 0.3833 mL 0.7667 mL 1.9167 mL
20 mM 0.0575 mL 0.2875 mL 0.5750 mL 1.4375 mL
25 mM 0.0460 mL 0.2300 mL 0.4600 mL 1.1500 mL
30 mM 0.0383 mL 0.1917 mL 0.3833 mL 0.9583 mL
40 mM 0.0287 mL 0.1437 mL 0.2875 mL 0.7187 mL
50 mM 0.0230 mL 0.1150 mL 0.2300 mL 0.5750 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cy5-PEG3-endo-BCN
Cat. No.:
HY-149618
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