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cycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive effects through binding of transcription factors.

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cycFWRPW Chemical Structure

cycFWRPW Chemical Structure

CAS No. : 2116533-34-5

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Description

cycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive effects through binding of transcription factors[1].

Molecular Weight

845.00

Formula

C46H56N10O6

CAS No.
Sequence

Phe-Trp-Arg-Pro-Trp (covalent bridge:Trp2-Pro4)

Sequence Shortening

FWRPW (covalent bridge:Trp2-Pro4)

SMILES

O=C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O)[C@@]3(CCCN3C([C@@H](NC([C@@H](NC([C@@H](N)CC4=CC=CC=C4)=O)C5)=O)CCCNC(N)=N)=O)CCCCN6C=C5C7=C6C=CC=C7

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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cycFWRPW
Cat. No.:
HY-P10488
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