Cyclo(Arg-Pro) (Synonyms: Cyclo(Pro-Arg))

Cat. No.: HY-P10304: FAQs
Data Sheet SDS Handling Instructions

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Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form.

For research use only. We do not sell to patients.

Cyclo(Arg-Pro) Chemical Structure

CAS No. : 74838-83-8

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5 mg		Ask For Quote & Lead Time
10 mg		Ask For Quote & Lead Time

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Description

Molecular Weight

253.30

Formula

C₁₁H₁₉N₅O₂

CAS No.

74838-83-8

Appearance

Solid

Color

White to off-white

Sequence

Cyclo(Arg-Pro)

Sequence Shortening

Cyclo(RP)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (986.97 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9479 mL	19.7394 mL	39.4789 mL
5 mM	0.7896 mL	3.9479 mL	7.8958 mL
10 mM	0.3948 mL	1.9739 mL	3.9479 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Data Sheet (269 KB) SDS (393 KB) Handling Instructions (2659 KB)

References

[1]. Izumida H, et al., The effect of chitinase inhibitors, cyclo(Arg-Pro) against cell separation of Saccharomyces cerevisiae and the morphological change of Candida albicans. J Antibiot (Tokyo). 1996 Aug;49(8):829-31. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.9479 mL	19.7394 mL	39.4789 mL	98.6972 mL
	5 mM	0.7896 mL	3.9479 mL	7.8958 mL	19.7394 mL
	10 mM	0.3948 mL	1.9739 mL	3.9479 mL	9.8697 mL
	15 mM	0.2632 mL	1.3160 mL	2.6319 mL	6.5798 mL
	20 mM	0.1974 mL	0.9870 mL	1.9739 mL	4.9349 mL
	25 mM	0.1579 mL	0.7896 mL	1.5792 mL	3.9479 mL
	30 mM	0.1316 mL	0.6580 mL	1.3160 mL	3.2899 mL
	40 mM	0.0987 mL	0.4935 mL	0.9870 mL	2.4674 mL
	50 mM	0.0790 mL	0.3948 mL	0.7896 mL	1.9739 mL
	60 mM	0.0658 mL	0.3290 mL	0.6580 mL	1.6450 mL
	80 mM	0.0493 mL	0.2467 mL	0.4935 mL	1.2337 mL
	100 mM	0.0395 mL	0.1974 mL	0.3948 mL	0.9870 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Cyclo(Arg-Pro) Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(Arg-Pro)74838-83-8Cyclo(Pro-Arg)FungalCandida albicansSaccharomyces cerevisiaeInhibitorinhibitorinhibit

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