2. NF-κB Metabolic Enzyme/Protease
  3. NF-κB Endogenous Metabolite
  4. Cyclo(his-pro) TFA (Standard)

Cyclo(his-pro) TFA (Standard)  (Synonyms: Cyclo(histidyl-proline) TFA (Standard); Histidylproline diketopiperazine TFA (Standard))

Cat. No.: HY-101402AR Purity: ≥98%
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Cyclo(his-pro) (TFA) (Standard) is the analytical standard of Cyclo(his-pro) (TFA). This product is intended for research and analytical applications. Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone[1]. Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses[2].

For research use only. We do not sell to patients.

Cyclo(his-pro) TFA (Standard) Chemical Structure

Cyclo(his-pro) TFA (Standard) Chemical Structure

CAS No. : 936749-56-3

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Description
Molecular Weight

348.28

Formula

C13H15F3N4O4
CAS No.
SMILES

OC(C(F)(F)F)=O.O=C(N[C@H]1CC2=CN=CN2)[C@@](CCC3)([H])N3C1=O
Structure Classification
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Cyclo(his-pro) TFA (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(his-pro) TFA (Standard)936749-56-3Cyclo(histidyl-proline) TFA (Standard)Histidylproline diketopiperazine TFA (Standard)NF-κBEndogenous MetaboliteNuclear factor-κBNuclear factor-kappaBorallyactivecyclicdipeptidetyreotropin-releasinghormonebrain-blood-barrierinflammatorystressresponsesInhibitorinhibitorinhibit

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