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  4. CypD-IN-29

CypD-IN-29 (compound 29) is an inhibitor of the Alzheimer's disease target CypD (KD=88.2 nM). CypD is a mitochondrial-specific cyclophilin that can bind to β-amyloid protein in brain mitochondria and promote the formation of mitochondrial permeability transition pore (mPTP).

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CypD-IN-29 Chemical Structure

CypD-IN-29 Chemical Structure

CAS No. : 1115335-95-9

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CypD-IN-29 Related Antibodies

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Description

CypD-IN-29 (compound 29) is an inhibitor of the Alzheimer's disease target CypD (KD=88.2 nM). CypD is a mitochondrial-specific cyclophilin that can bind to β-amyloid protein in brain mitochondria and promote the formation of mitochondrial permeability transition pore (mPTP).

Molecular Weight

485.53

Formula

C26H20FN5O2S
CAS No.
SMILES

O=C(NCC1=CC=C(F)C=C1)C2=CC=CC(N3C=CN=C3SCC(NC4=CC=CC=C4C#N)=O)=C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CypD-IN-29 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CypD-IN-291115335-95-9OthersInhibitorinhibitorinhibit

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