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  3. Amino Acid Derivatives
  4. CyPep-1

CyPep-1 is a novel cationic lytic peptide with antitumor activity. CyPep-1 is highly cytotoxic by interacting with the negatively charged cell membrane of cancer cells. CyPep-1 has strong cytolytic activity on cancer cells both in vivo and in vitro, and can be used in the study of solid tumors.

For research use only. We do not sell to patients.

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CyPep-1 Chemical Structure

CyPep-1 Chemical Structure

CAS No. : 1319804-91-5

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CyPep-1 Related Antibodies

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Description

CyPep-1 is a novel cationic lytic peptide with antitumor activity. CyPep-1 is highly cytotoxic by interacting with the negatively charged cell membrane of cancer cells. CyPep-1 has strong cytolytic activity on cancer cells both in vivo and in vitro, and can be used in the study of solid tumors[1].

In Vitro

CyPep-1 (0-40 μg/mL; 15-360 min) produces toxicity to tumor cell lines in a dose- and time-dependent manner, with little effect on normal cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CyPep-1 Related Antibodies
In Vivo

CyPep-1 (intratumoral injection; 1200 µg; single dose) has antitumor effect in mouse model of breast cancer[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4T1 murine metastatic breast cancer cells treated female BALB/c mice (average age 12625 days; average weight 23.8g)[1]
Dosage: 1200 µg
Administration: Intratumoural injection; single dose
Result: Did not cause any signs of discomfort, pain or toxicity.
Significantly reduced tumour growth and caused massive necrosis of the tumours.
Prolonged the median survival time of mice.
Molecular Weight

3451.09

Formula

C152H265N57O35
CAS No.
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Lys-Thr-Leu-Arg-Val-Ala-Lys-Ala-Ile-Tyr-Lys-Arg-Tyr-Ile-Glu
Sequence Shortening

YGRKKRRQRRRGKTLRVAKAIYKRYIE
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CyPep-1 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CyPep-11319804-91-5CyPep1CyPep 1Amino Acid DerivativesBreast cancer modelosteosarcoma cellsglioma cellsInhibitorinhibitorinhibit

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