2. GPCR/G Protein
  3. Leukotriene Receptor
  4. CysLT1 receptor antagonist-1

CysLT1 receptor antagonist-1 (Compound 4) is an antagonist for cysteinyl leukotriene receptor 1 (CysLT1R) with an IC50 of 3.9 μM. CysLT1 receptor antagonist-1 exhibits weak agonist activity against G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficact of 23% at 10 μM. CysLT1 receptor antagonist-1 can be used for asthma and allergic diseases researchs.

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CysLT1 receptor antagonist-1 Chemical Structure

CysLT1 receptor antagonist-1 Chemical Structure

CAS No. : 119515-00-3

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CysLT1 receptor antagonist-1 Related Antibodies

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Description

CysLT1 receptor antagonist-1 (Compound 4) is an antagonist for cysteinyl leukotriene receptor 1 (CysLT1R) with an IC50 of 3.9 μM. CysLT1 receptor antagonist-1 exhibits weak agonist activity against G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficact of 23% at 10 μM. CysLT1 receptor antagonist-1 can be used for asthma and allergic diseases researchs[1].

IC50 & Target

CysLT1

3.9 μM (IC50)

Molecular Weight

293.32

Formula

C18H15NO3
CAS No.
SMILES

O=C(C1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1)OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CysLT1 receptor antagonist-1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CysLT1 receptor antagonist-1119515-00-3Leukotriene ReceptorAsthmaallergyInhibitorinhibitorinhibit

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