Cytochalasin J

Cat. No.: HY-126556: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Cytochalasin J is a cytochalasin detivative. Cytochalasin J affects mitotic spindel microtubule organization and kinetochore structure, and exhibits cytotoxicity in human leukemia K562 cell with IC₅₀ of 1.5 μM.

For research use only. We do not sell to patients.

Cytochalasin J Chemical Structure

CAS No. : 53760-20-6

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 50 μM Compound: 17	Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 35473314]
HepG2	IC₅₀	> 50 μM Compound: 17	Cytotoxicity against human HepG2 cells measured after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells measured after 72 hrs by MTT assay	[PMID: 35473314]
MDA-MB-231	IC₅₀	31 μM Compound: 17	Cytotoxicity against human MDA-MB-231 cells measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells measured after 72 hrs by MTT assay	[PMID: 35473314]
MDA-MB-435	IC₅₀	4.9 μM Compound: 17	Cytotoxicity against human MDA-MB-435 cells measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells measured after 72 hrs by MTT assay	[PMID: 35473314]
SNB-19	IC₅₀	6.8 μM Compound: 17	Cytotoxicity against human SNB-19 cells measured after 72 hrs by MTT assay Cytotoxicity against human SNB-19 cells measured after 72 hrs by MTT assay	[PMID: 35473314]
Vero	IC₅₀	> 50 μM Compound: 17	Cytotoxicity against African green monkey Vero cells measured after 72 hrs by MTT assay Cytotoxicity against African green monkey Vero cells measured after 72 hrs by MTT assay	[PMID: 35473314]

Molecular Weight

451.60

Formula

C₂₈H₃₇NO₄

CAS No.

53760-20-6

SMILES

O=C([C@@]12[C@](/C=C/C[C@H](C)C[C@@](C)(O)/C=C/[C@H]2O)([H])[C@@H]3O)N[C@@H](CC4=CC=CC=C4)[C@]1([H])[C@H](C)C3=C

Structure Classification

Others

Initial Source

Microorganisms

Endothia gyrosa IFB-E023

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xu S, et al., Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa. Chem Biodivers. 2009 May;6(5):739-45. [Content Brief]

[2]. Wrench GA, et al., Cytochalasin J treatment significantly alters mitotic spindle microtubule organization and kinetochore structure in PtK1 cells. Cell Motil Cytoskeleton. 1997;36(2):112-24. [Content Brief]

Cytochalasin J Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cytochalasin J53760-20-6Microtubule/TubulinPtK1K562Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks