2. Metabolic Enzyme/Protease Apoptosis
  3. Phosphatase Apoptosis
  4. Cytostatin

Cytostatin is an effective and selective protein phosphatase 2A (PP2A) inhibitor with an IC50 value of 210 nM. Cytostatin exhibits anti-metastatic properties, good antitumor activity, and can induce apoptosis. Cytostatin can also prevent the adhesion of B16 melanoma cells to components of the extracellular matrix (laminin and collagen). Cytostatin belongs to the family of natural product fosriecin.

For research use only. We do not sell to patients.

Cytostatin Chemical Structure

Cytostatin Chemical Structure

CAS No. : 682329-63-1

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Other Forms of Cytostatin:

Cytostatin Related Antibodies

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Description

Cytostatin is an effective and selective protein phosphatase 2A (PP2A) inhibitor with an IC50 value of 210 nM. Cytostatin exhibits anti-metastatic properties, good antitumor activity, and can induce apoptosis. Cytostatin can also prevent the adhesion of B16 melanoma cells to components of the extracellular matrix (laminin and collagen). Cytostatin belongs to the family of natural product fosriecin[1][2][3][4].

IC50 & Target

PP2A[1]
Molecular Weight

428.46

Formula

C21H33O7P
CAS No.
SMILES

O=C1C=C[C@H](C)[C@H]([C@@H](C)CC[C@H](OP(O)(O)=O)[C@@H](C)[C@@H](O)/C=C\C=C/C=C/C)O1
Structure Classification
Initial Source

fostriecin
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cytostatin Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cytostatin682329-63-1PhosphataseApoptosisPP2Aantitumornatural productsB16 melanoma cellsapoptosisInhibitorinhibitorinhibit

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