2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite Phospholipase
  4. D-Erythro-dihydrosphingosine-d7

D-Erythro-dihydrosphingosine-d7  (Synonyms: Sphinganine (d18:0)-d7)

Cat. No.: HY-W019838S Purity: 99.00%
COA Handling Instructions

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D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.

For research use only. We do not sell to patients.

D-Erythro-dihydrosphingosine-d<sub>7</sub> Chemical Structure

D-Erythro-dihydrosphingosine-d7 Chemical Structure

CAS No. : 1246304-35-7

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500 μg USD 293 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of D-Erythro-dihydrosphingosine-d7:

D-Erythro-dihydrosphingosine-d7 Related Antibodies

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Description

D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

D-Erythro-dihydrosphingosine-d7 Related Antibodies
Molecular Weight

308.55

Formula

C18H32D7NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 10 mg/mL (32.41 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2410 mL 16.2048 mL 32.4097 mL
5 mM 0.6482 mL 3.2410 mL 6.4819 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.00%

COA (241 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 3.2410 mL 16.2048 mL 32.4097 mL 81.0241 mL
5 mM 0.6482 mL 3.2410 mL 6.4819 mL 16.2048 mL
10 mM 0.3241 mL 1.6205 mL 3.2410 mL 8.1024 mL
15 mM 0.2161 mL 1.0803 mL 2.1606 mL 5.4016 mL
20 mM 0.1620 mL 0.8102 mL 1.6205 mL 4.0512 mL
25 mM 0.1296 mL 0.6482 mL 1.2964 mL 3.2410 mL
30 mM 0.1080 mL 0.5402 mL 1.0803 mL 2.7008 mL
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D-Erythro-dihydrosphingosine-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Erythro-dihydrosphingosine-d71246304-35-7Sphinganine (d18:0)-d7Isotope-Labeled CompoundsEndogenous MetabolitePhospholipaseInhibitorinhibitorinhibit

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