1. Cell Cycle/DNA Damage
  2. RAD51
  3. D-G23

D-G23 is a selective RAD52 inhibitor. D-G23 disrupts RAD52-mediated DNA repair pathways and suppresses the growth of BRCA1- and BRCA2-deficient cancer cells. D-G23 is promising for research of homologous recombination-related cancers, such as hereditary breast cancer and ovarian cancer caused by BRCA1/2 mutations.

For research use only. We do not sell to patients.

D-G23 Chemical Structure

D-G23 Chemical Structure

CAS No. : 1225141-73-0

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Description

D-G23 is a selective RAD52 inhibitor. D-G23 disrupts RAD52-mediated DNA repair pathways and suppresses the growth of BRCA1- and BRCA2-deficient cancer cells. D-G23 is promising for research of homologous recombination-related cancers, such as hereditary breast cancer and ovarian cancer caused by BRCA1/2 mutations[1].

Molecular Weight

354.40

Formula

C19H22N4O3

CAS No.
SMILES

OCCCNC1=C2C=CC=CC2=NC(NC3=CC(OC)=CC=C3OC)=N1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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D-G23
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HY-122583
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