1. GPCR/G Protein PI3K/Akt/mTOR
  2. GLP Receptor Akt
  3. d-GLP-2 E33A

d-GLP-2 E33A is an agonist for the glucagon-like peptide 2 receptor (GLP-2R) with an EC50 of 414 nM. d-GLP-2 E33A can activate GLP-2R and increase the phosphorylation of AKT, but has no stimulative effect on GLP-1R. d-GLP-2 E33A can be used in the study of diseases such as intestinal malabsorption and inflammatory bowel diseases.

For research use only. We do not sell to patients.

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d-GLP-2 E33A Chemical Structure

d-GLP-2 E33A Chemical Structure

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Description

d-GLP-2 E33A is an agonist for the glucagon-like peptide 2 receptor (GLP-2R) with an EC50 of 414 nM. d-GLP-2 E33A can activate GLP-2R and increase the phosphorylation of AKT, but has no stimulative effect on GLP-1R. d-GLP-2 E33A can be used in the study of diseases such as intestinal malabsorption and inflammatory bowel diseases[1].

IC50 & Target

EC50: 414 nM (GLP-2R)[1]

Molecular Weight

3685.26

Formula

C170H263N47O43S

Sequence

Ac-Ile-Lys-Ala-Gln-Trp-Leu-Ala-Ala-Glu-Phe-Ile-Gln-Ala-Val-Ala-Ala-Val-Leu-Ala-Met-Leu-Arg-Asn-Asn-Gln-Phe-Glu-Phe-Ala-Gly-Val-Ala-His-NH-NH2

Sequence Shortening

Ac-IKAQWLAAEFIQAVAAVLAMLRNNQFEFAGVAH-NH-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
d-GLP-2 E33A
Cat. No.:
HY-P10842
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