2. GPCR/G Protein
  3. GnRH Receptor
  4. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist.

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[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH Chemical Structure

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH Chemical Structure

CAS No. : 68059-94-9

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[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH Related Antibodies

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Description

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist[1].

IC50 & Target

GnRH receptor[1]
In Vitro

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH (1 μM), together with LH-RH and FSH, blocks the inhibition of FSH-induced steroidogenesis in rat ovary granulosa cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH Related Antibodies
In Vivo

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH (1.25 and 2.5 mg, subcutaneous injection, b.i.d, for 7 days) prolongs pregnancy in rats[1].
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH (250 μg) inhibits ovulation by 100% in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1321.48

Formula

C67H84N16O13
CAS No.
Sequence Shortening

{d-Glp}-{d-Phe}-{d-Trp}-SY-{d-Trp}-LRPG-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH68059-94-9GnRH ReceptorGonadotropin releasing hormone receptorGNRHRLHRHLHRH analoguepregnancyovulationInhibitorinhibitorinhibit

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