D-Ile-Pro-Arg p-nitroanilide dihydrochloride

Cat. No.: HY-137837 Purity: 99.87%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA).

For research use only. We do not sell to patients.

D-Ile-Pro-Arg p-nitroanilide dihydrochloride Chemical Structure

CAS No. : 96323-41-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Biological Activity
Purity & Documentation
References
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Description

D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA)^[1].

Molecular Weight

577.50

Formula

C₂₃H₃₈Cl₂N₈O₅

CAS No.

96323-41-0

Appearance

Solid

Color

White to off-white

SMILES

[O-][N+](C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](N)[C@H](C)CC)=O)=O)=O)=O.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (173.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 100 mg/mL (173.16 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7316 mL	8.6580 mL	17.3160 mL
5 mM	0.3463 mL	1.7316 mL	3.4632 mL
10 mM	0.1732 mL	0.8658 mL	1.7316 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.87%

Select Batch:

Data Sheet (271 KB) SDS (558 KB)

COA (253 KB) RP-HPLC (109 KB) MS (229 KB)

Handling Instructions (2659 KB)

References

[1]. Chmielewska J, et al. Kinetics of the inhibition of plasminogen activators by the plasminogen-activator inhibitor. Evidence for 'second-site' interactions. Biochem J. 1988 Apr 15;251(2):327-32. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	1.7316 mL	8.6580 mL	17.3160 mL	43.2900 mL
	5 mM	0.3463 mL	1.7316 mL	3.4632 mL	8.6580 mL
	10 mM	0.1732 mL	0.8658 mL	1.7316 mL	4.3290 mL
	15 mM	0.1154 mL	0.5772 mL	1.1544 mL	2.8860 mL
	20 mM	0.0866 mL	0.4329 mL	0.8658 mL	2.1645 mL
	25 mM	0.0693 mL	0.3463 mL	0.6926 mL	1.7316 mL
	30 mM	0.0577 mL	0.2886 mL	0.5772 mL	1.4430 mL
	40 mM	0.0433 mL	0.2165 mL	0.4329 mL	1.0823 mL
	50 mM	0.0346 mL	0.1732 mL	0.3463 mL	0.8658 mL
	60 mM	0.0289 mL	0.1443 mL	0.2886 mL	0.7215 mL
	80 mM	0.0216 mL	0.1082 mL	0.2165 mL	0.5411 mL
	100 mM	0.0173 mL	0.0866 mL	0.1732 mL	0.4329 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.