2. Apoptosis
  3. Apoptosis
  4. DB2313 tetrahydrochloride

DB2313 tetrahydrochloride is a potent transcription factor PU.1 inhibitor with an apoptosis of 14 nM. DB2313 tetrahydrochloride disrupts the interaction of PU.1 with target gene promoters. DB2313 tetrahydrochloride induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects.

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DB2313 tetrahydrochloride Chemical Structure

DB2313 tetrahydrochloride Chemical Structure

CAS No. : 2170606-75-2

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Other Forms of DB2313 tetrahydrochloride:

DB2313 tetrahydrochloride Related Antibodies

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Description

DB2313 tetrahydrochloride is a potent transcription factor PU.1 inhibitor with an apoptosis of 14 nM. DB2313 tetrahydrochloride disrupts the interaction of PU.1 with target gene promoters. DB2313 tetrahydrochloride induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects[1].

Molecular Weight

854.67

Formula

C42H45Cl4FN8O2
CAS No.
SMILES

FC1=C(COC2=CC=C(C3=NC4=CC=C(C(NC(C)C)=N)C=C4N3)C=C2)C=CC=C1COC5=CC=C(C6=NC7=CC=C(C(NC(C)C)=N)C=C7N6)C=C5.Cl.Cl.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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DB2313 tetrahydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DB2313 tetrahydrochloride2170606-75-2ApoptosisPU.1DNAanticanceracutemyeloidleukemiaInhibitorinhibitorinhibit

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