1. Anti-infection
  2. Enterovirus
  3. DC07090

DC07090 is a novel and potent small molecule inhibitor targeting the human enterovirus EV71 3C protease, with an IC50 value of 21.72 μM and no significant toxicity, as indicated by a CC50 greater than 200 μM. DC07090 can inhibit EV71 replication, with an EC50 value of 22.09 μM and a Ki value of 23.29 μM. DC07090 also inhibits the replication of Coxsackievirus A16 (CVA16), showing an EC50 value of 27.76 μM.

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DC07090 Chemical Structure

DC07090 Chemical Structure

CAS No. : 879070-72-1

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Description

DC07090 is a novel and potent small molecule inhibitor targeting the human enterovirus EV71 3C protease, with an IC50 value of 21.72 μM and no significant toxicity, as indicated by a CC50 greater than 200 μM. DC07090 can inhibit EV71 replication, with an EC50 value of 22.09 μM and a Ki value of 23.29 μM. DC07090 also inhibits the replication of Coxsackievirus A16 (CVA16), showing an EC50 value of 27.76 μM[1].

Molecular Weight

302.33

Formula

C18H14N4O

CAS No.
SMILES

N1C2N=CC=CC=2OC=1C1C=CC(=CC=1)NCC1C=CC=CN=1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DC07090
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HY-Q43250
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