DCVC-¹³C₃,¹⁵N (Synonyms: S-[(1E)-1,2-Dichloroethenyl]-L-cysteine-¹³C₃,¹⁵N)

Cat. No.: HY-19717S: FAQs
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DCVC-¹³C₃,¹⁵N is ¹⁵N and ¹³C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures.

For research use only. We do not sell to patients.

DCVC-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N Chemical Structure

DCVC-¹³C₃,¹⁵N Chemical Structure

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1 mg		Get quote	Estimated Time of Arrival: December 31

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Description	DCVC-¹³C₃,¹⁵N is ¹⁵N and ¹³C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures^[1]^[2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. DCVC-¹³C₃,¹⁵N Related Antibodies
Molecular Weight	220.06
Formula	C₂¹³C₃H₇Cl₂¹⁵NO₂S
Unlabeled CAS	13419-46-0
SMILES	[15NH2][13C@H]([13C](O)=O)[13CH2]S/C(Cl)=C\Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

DCVC-¹³C₃,¹⁵N Related Classifications

Inflammation/Immunology

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCVC-¹³C₃,¹⁵NS-[(1E)-1,2-Dichloroethenyl]-L-cysteine-¹³C₃,¹⁵NIsotope-Labeled CompoundsExtraplacentalmembranestrichloroethyleneimmuneIL-1βIL-8 TNF-αnephrotoxicantInhibitorinhibitorinhibit

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DCVC-13C3,15N (Synonyms: S-[(1E)-1,2-Dichloroethenyl]-L-cysteine-13C3,15N)

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