Desisobutyryl ciclesonide-d₁₁ 

Desisobutyryl ciclesonide-d₁₁ is the deuterium labeled Desisobutyryl ciclesonide[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

481.67

C₂₈H₂₇D₁₁O₆

Solid

White to off-white

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(C6([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C6([2H])[2H])O2)C)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]