Di-O-methylhonokiol

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Di-O-methylhonokiol is a natural phenolic compound that can be isolated from magnolia flowers. Di-O-methylhonokiol has significant antibacterial activity against Gram-positive bacteria, acid-fast bacilli, and yeast-like and filamentous fungi. Di-O-methylhonokiol can be used in the study of fungal infections.

For research use only. We do not sell to patients.

Di-O-methylhonokiol Chemical Structure

CAS No. : 68592-18-7

Size	Price	Stock	Quantity
1 mg	USD 120	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	USD 300	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	USD 475	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CNE2Z	IC₅₀	> 50 μM Compound: 1c	Antiproliferative activity against human CNE2Z cells assessed as growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human CNE2Z cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 31831382]
HepG2	IC₅₀	> 135.98 μM Compound: 9i	Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 21853991]
HUVEC	IC₅₀	> 100 μM Compound: 9i	Antiproliferative activity against human HUVEC cells after 24 hrs by MTT assay Antiproliferative activity against human HUVEC cells after 24 hrs by MTT assay	[PMID: 21853991]
I10	IC₅₀	> 50 μM Compound: 1c	Antiproliferative activity against mouse I10 cells assessed as growth inhibition after 72 hrs by MTT assay Antiproliferative activity against mouse I10 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 31831382]
Lewis lung carcinoma cell line	IC₅₀	> 136 μM Compound: 9i	Antiproliferative activity against mouse LL/2 cells after 24 hrs by MTT assay Antiproliferative activity against mouse LL/2 cells after 24 hrs by MTT assay	[PMID: 21853991]
MCF7	IC₅₀	> 50 μM Compound: 1c	Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 31831382]
Oocyte	EC₅₀	42.1 μM Compound: 13	Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique	[PMID: 21699169]
RAW264.7	IC₅₀	> 100 μM Compound: 5	Cytotoxicity against mouse RAW264.7 cells assessed as cell viability by propidium iodide staining based FACS-flow cytometry Cytotoxicity against mouse RAW264.7 cells assessed as cell viability by propidium iodide staining based FACS-flow cytometry	[PMID: 22494844]
RAW264.7	IC₅₀	40 μM Compound: 5	Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess assay Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess assay	[PMID: 22494844]

Molecular Weight

294.39

Formula

C₂₀H₂₂O₂

CAS No.

68592-18-7

SMILES

COC1=C(CC=C)C=C(C=C1)C2=CC(CC=C)=CC=C2OC

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. A M Clark, et al. Antimicrobial activity of phenolic constituents of Magnolia grandiflora L. J Pharm Sci. 1981 Aug;70(8):951-2. [Content Brief]

[2]. Clark A M, et al. Antimicrobial activity of phenolic constituents of Magnolia grandiflora L[J]. Journal of pharmaceutical sciences, 1981, 70(8): 951-952. [Content Brief]