2. Anti-infection
  3. Bacterial
  4. Diazaborine

Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL.

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Diazaborine Chemical Structure

Diazaborine Chemical Structure

CAS No. : 22959-81-5

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10 mg USD 110 In-stock
25 mg USD 220 In-stock
50 mg USD 350 In-stock
100 mg USD 550 In-stock
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Diazaborine Related Antibodies

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Description

Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL[1].

Molecular Weight

300.14

Formula

C14H13BN2O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(N1B(C2=CC=CC=C2C=N1)O)(C3=CC=C(C)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (111.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3318 mL 16.6589 mL 33.3178 mL
5 mM 0.6664 mL 3.3318 mL 6.6636 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3318 mL 16.6589 mL 33.3178 mL 83.2945 mL
5 mM 0.6664 mL 3.3318 mL 6.6636 mL 16.6589 mL
10 mM 0.3332 mL 1.6659 mL 3.3318 mL 8.3294 mL
15 mM 0.2221 mL 1.1106 mL 2.2212 mL 5.5530 mL
20 mM 0.1666 mL 0.8329 mL 1.6659 mL 4.1647 mL
25 mM 0.1333 mL 0.6664 mL 1.3327 mL 3.3318 mL
30 mM 0.1111 mL 0.5553 mL 1.1106 mL 2.7765 mL
40 mM 0.0833 mL 0.4165 mL 0.8329 mL 2.0824 mL
50 mM 0.0666 mL 0.3332 mL 0.6664 mL 1.6659 mL
60 mM 0.0555 mL 0.2776 mL 0.5553 mL 1.3882 mL
80 mM 0.0416 mL 0.2082 mL 0.4165 mL 1.0412 mL
100 mM 0.0333 mL 0.1666 mL 0.3332 mL 0.8329 mL
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Diazaborine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diazaborine22959-81-5BacterialK. PneumoniaeE. coliantibacterialInhibitorinhibitorinhibit

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