2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Dideoxycytidinene

Dideoxycytidinene  (Synonyms: 2′,3′-Didehydro-2′,3′-dideoxycytidine)

Cat. No.: HY-145791 Purity: 98.36%
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Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

Dideoxycytidinene Chemical Structure

Dideoxycytidinene Chemical Structure

CAS No. : 7481-88-1

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Based on 1 publication(s) in Google Scholar

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Dideoxycytidinene Related Antibodies

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Description

Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 ED50
10 nM
Compound: 1
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
[PMID: 8627596]
HepG2 ED50
8 nM
Compound: 1
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
[PMID: 8627596]
Molecular Weight

209.20

Formula

C9H11N3O3
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

OC[C@@H]1C=C[C@H](N2C(N=C(N)C=C2)=O)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Dideoxycytidinene Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dideoxycytidinene7481-88-12′,3′-Didehydro-2′,3′-dideoxycytidineNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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