1. PROTAC
  2. PROTAC Linkers
  3. Diethylene Glycol Monobenzyl Ether

Diethylene Glycol Monobenzyl Ether 

Cat. No.: HY-22393 Purity: 97.41%
SDS COA Handling Instructions

Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Diethylene Glycol Monobenzyl Ether Chemical Structure

Diethylene Glycol Monobenzyl Ether Chemical Structure

CAS No. : 2050-25-1

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Description

Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

196.24

Formula

C11H16O3

CAS No.
Appearance

Liquid (Density: 1.094 g/cm3)

Color

Colorless to light yellow

SMILES

OCCOCCOCC1=CC=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Diethylene Glycol Monobenzyl Ether Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Diethylene Glycol Monobenzyl Ether
Cat. No.:
HY-22393
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