2. Protein Tyrosine Kinase/RTK Others
  3. Btk Isotope-Labeled Compounds
  4. Dihydrodiol-Ibrutinib-d5

Dihydrodiol-Ibrutinib-d5  (Synonyms: PCI-45227-d5)

Cat. No.: HY-100659S
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Dihydrodiol-Ibrutinib-d5 is the deuterium labeled Dihydrodiol-Ibrutinib (HY-100659). Dihydrodiol-Ibrutinib is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib.

For research use only. We do not sell to patients.

Dihydrodiol-Ibrutinib-d<sub>5</sub> Chemical Structure

Dihydrodiol-Ibrutinib-d5 Chemical Structure

CAS No. : 2068022-09-1

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Dihydrodiol-Ibrutinib-d5 Related Antibodies

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Description

Dihydrodiol-Ibrutinib-d5 is the deuterium labeled Dihydrodiol-Ibrutinib (HY-100659). Dihydrodiol-Ibrutinib is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib[1].

Molecular Weight

479.54

Formula

C25H21D5N6O4
CAS No.
Unlabeled CAS

1226872-27-0
SMILES

NC1=C2C(N([C@@]3([H])CN(CCC3)C(C(O)CO)=O)N=C2C4=CC=C(C=C4)OC5=C([2H])C([2H])=C([2H])C([2H])=C5[2H])=NC=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dihydrodiol-Ibrutinib-d5 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydrodiol-Ibrutinib-d52068022-09-1PCI-45227-d5BtkIsotope-Labeled CompoundsBruton tyrosine kinaseBTKmetabolitedihydrodiolInhibitorinhibitorinhibit

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