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  3. Dipropylenetriamine NONOate

Dipropylenetriamine NONOate  (Synonyms: DPTA-NO)

Cat. No.: HY-W507393
Handling Instructions Technical Support

Dipropylenetriamine NONOate (DPTA-NO) is a NO donor, which spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively.

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Dipropylenetriamine NONOate Chemical Structure

Dipropylenetriamine NONOate Chemical Structure

CAS No. : 146724-95-0

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Based on 1 publication(s) in Google Scholar

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Description

Dipropylenetriamine NONOate (DPTA-NO) is a NO donor, which spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively[1][2].

Molecular Weight

191.23

Formula

C6H17N5O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C(CN)CN(CCCN)/[N+](=N/O)/[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 125 mg/mL (653.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2293 mL 26.1465 mL 52.2930 mL
5 mM 1.0459 mL 5.2293 mL 10.4586 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2293 mL 26.1465 mL 52.2931 mL 130.7326 mL
5 mM 1.0459 mL 5.2293 mL 10.4586 mL 26.1465 mL
10 mM 0.5229 mL 2.6147 mL 5.2293 mL 13.0733 mL
15 mM 0.3486 mL 1.7431 mL 3.4862 mL 8.7155 mL
20 mM 0.2615 mL 1.3073 mL 2.6147 mL 6.5366 mL
25 mM 0.2092 mL 1.0459 mL 2.0917 mL 5.2293 mL
30 mM 0.1743 mL 0.8716 mL 1.7431 mL 4.3578 mL
40 mM 0.1307 mL 0.6537 mL 1.3073 mL 3.2683 mL
50 mM 0.1046 mL 0.5229 mL 1.0459 mL 2.6147 mL
60 mM 0.0872 mL 0.4358 mL 0.8716 mL 2.1789 mL
80 mM 0.0654 mL 0.3268 mL 0.6537 mL 1.6342 mL
100 mM 0.0523 mL 0.2615 mL 0.5229 mL 1.3073 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dipropylenetriamine NONOate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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