2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. DL-01 TFA

DL-01 TFA is the TFA salt form of DL-01 (HY-155870). DL-01 TFA is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs.

For research use only. We do not sell to patients.

DL-01 TFA Chemical Structure

DL-01 TFA Chemical Structure

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Other Forms of DL-01 TFA:

DL-01 TFA Related Antibodies

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Description

DL-01 TFA is the TFA salt form of DL-01 (HY-155870). DL-01 TFA is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs[1].

Molecular Weight

1212.29

Formula

C57H72F3N9O15S
Appearance

Solid

Color

Light yellow to yellow

SMILES

CS(C1=NC=C(C=N1)C#CCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCCN(CCC)CCC)C(NCC(NCOCCCC2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(OCO7)=C7C=C62)=O)=O)=O)=O)(=O)=O.OC(C(F)(F)F)=O
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light, stored under nitrogen
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (82.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8249 mL 4.1244 mL 8.2489 mL
5 mM 0.1650 mL 0.8249 mL 1.6498 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8249 mL 4.1244 mL 8.2489 mL 20.6221 mL
5 mM 0.1650 mL 0.8249 mL 1.6498 mL 4.1244 mL
10 mM 0.0825 mL 0.4124 mL 0.8249 mL 2.0622 mL
15 mM 0.0550 mL 0.2750 mL 0.5499 mL 1.3748 mL
20 mM 0.0412 mL 0.2062 mL 0.4124 mL 1.0311 mL
25 mM 0.0330 mL 0.1650 mL 0.3300 mL 0.8249 mL
30 mM 0.0275 mL 0.1375 mL 0.2750 mL 0.6874 mL
40 mM 0.0206 mL 0.1031 mL 0.2062 mL 0.5156 mL
50 mM 0.0165 mL 0.0825 mL 0.1650 mL 0.4124 mL
60 mM 0.0137 mL 0.0687 mL 0.1375 mL 0.3437 mL
80 mM 0.0103 mL 0.0516 mL 0.1031 mL 0.2578 mL
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DL-01 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-01DL01DL 01Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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