DL-Metanephrine hydrochloride (a,b,b-d₃, 98%)

Name: DL-Metanephrine hydrochloride (a,b,b-d 3 , 98%)
Brand: MedChemExpress
SKU: HY-W012206S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-W012206S1 Purity: 99.34%: FAQs
Data Sheet SDS COA Handling Instructions

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DL-Metanephrine (hydrochloride) (a,b,b-d₃, 98%) is the deuterium labeled DL-Metanephrine (hydrochloride) (a,b,b, 98%)[1].

For research use only. We do not sell to patients.

DL-Metanephrine hydrochloride (a,b,b-d<sub>3</sub>, 98%) Chemical Structure

DL-Metanephrine hydrochloride (a,b,b-d₃, 98%) Chemical Structure

CAS No. : 1085333-94-3

Size	Price	Stock	Quantity
1 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 750	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Metanephrine hydrochloride (a,b,b-d₃, 98%):

(Rac)-Metanephrine hydrochloride Get quote

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Purity & Documentation
References
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Description

DL-Metanephrine (hydrochloride) (a,b,b-d₃, 98%) is the deuterium labeled DL-Metanephrine (hydrochloride) (a,b,b, 98%)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

236.71

Formula

C₁₀H₁₃D₃ClNO₃

CAS No.

1085333-94-3

Appearance

Solid

Color

White to off-white

SMILES

CNC([2H])([2H])C(C1=CC(OC)=C(C=C1)O)([2H])O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 12 mg/mL (50.69 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.2246 mL	21.1229 mL	42.2458 mL
5 mM	0.8449 mL	4.2246 mL	8.4492 mL
10 mM	0.4225 mL	2.1123 mL	4.2246 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (251 KB) HNMR (178 KB) RP-HPLC (212 KB) MS (169 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.2246 mL	21.1229 mL	42.2458 mL	105.6145 mL
	5 mM	0.8449 mL	4.2246 mL	8.4492 mL	21.1229 mL
	10 mM	0.4225 mL	2.1123 mL	4.2246 mL	10.5614 mL
	15 mM	0.2816 mL	1.4082 mL	2.8164 mL	7.0410 mL
	20 mM	0.2112 mL	1.0561 mL	2.1123 mL	5.2807 mL
	25 mM	0.1690 mL	0.8449 mL	1.6898 mL	4.2246 mL
	30 mM	0.1408 mL	0.7041 mL	1.4082 mL	3.5205 mL
	40 mM	0.1056 mL	0.5281 mL	1.0561 mL	2.6404 mL
	50 mM	0.0845 mL	0.4225 mL	0.8449 mL	2.1123 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.