DMPQ dihydrochloride

Cat. No.: HY-108627 Purity: 99.10%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC₅₀ of 80 nM.

For research use only. We do not sell to patients.

DMPQ dihydrochloride Chemical Structure

CAS No. : 1123491-15-5

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Biological Activity
Purity & Documentation
References
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Description

DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC₅₀ of 80 nM^[1].

Molecular Weight

339.22

Formula

C₁₆H₁₆Cl₂N₂O₂

CAS No.

1123491-15-5

Appearance

Solid

Color

Light yellow to yellow

SMILES

COC1=CC(OC)=C2C=C(C3=CC=NC=C3)C=NC2=C1.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (294.79 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9479 mL	14.7397 mL	29.4794 mL
5 mM	0.5896 mL	2.9479 mL	5.8959 mL
10 mM	0.2948 mL	1.4740 mL	2.9479 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.10%

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Data Sheet (270 KB) SDS (392 KB)

COA (250 KB) HNMR (141 KB) RP-HPLC (140 KB) LCMS (105 KB)

Handling Instructions (2659 KB)

References

[1]. Dolle RE, et al. 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 1994 Aug 19;37(17):2627-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.9479 mL	14.7397 mL	29.4794 mL	73.6985 mL
	5 mM	0.5896 mL	2.9479 mL	5.8959 mL	14.7397 mL
	10 mM	0.2948 mL	1.4740 mL	2.9479 mL	7.3698 mL
	15 mM	0.1965 mL	0.9826 mL	1.9653 mL	4.9132 mL
	20 mM	0.1474 mL	0.7370 mL	1.4740 mL	3.6849 mL
	25 mM	0.1179 mL	0.5896 mL	1.1792 mL	2.9479 mL
	30 mM	0.0983 mL	0.4913 mL	0.9826 mL	2.4566 mL
	40 mM	0.0737 mL	0.3685 mL	0.7370 mL	1.8425 mL
	50 mM	0.0590 mL	0.2948 mL	0.5896 mL	1.4740 mL
	60 mM	0.0491 mL	0.2457 mL	0.4913 mL	1.2283 mL
	80 mM	0.0368 mL	0.1842 mL	0.3685 mL	0.9212 mL
	100 mM	0.0295 mL	0.1474 mL	0.2948 mL	0.7370 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.