1. NF-κB
  2. IKK
  3. DMX-129

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε.

For research use only. We do not sell to patients.

DMX-129 Chemical Structure

DMX-129 Chemical Structure

CAS No. : 1623123-95-4

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Description

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].

IC50 & Target

IC50: <30 nM (TBK-1), <30 nM (ΙΚΚε)[1]

Molecular Weight

376.39

Formula

C19H17FN8

CAS No.
SMILES

N#CC1=C(N2CC[C@@H](C2)F)N=CC(C3=NC(NC4=CN=C(N)C=C4)=NC=C3)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DMX-129
Cat. No.:
HY-148206
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