2. NF-κB
  3. IKK
  4. DMX-129

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε.

For research use only. We do not sell to patients.

DMX-129 Chemical Structure

DMX-129 Chemical Structure

CAS No. : 1623123-95-4

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DMX-129 Related Antibodies

Top Publications Citing Use of Products

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IKK-α IKK-β IKK IKKε TBK1

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Description

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].

IC50 & Target

IC50: <30 nM (TBK-1), <30 nM (ΙΚΚε)[1]
Molecular Weight

376.39

Formula

C19H17FN8
CAS No.
SMILES

N#CC1=C(N2CC[C@@H](C2)F)N=CC(C3=NC(NC4=CN=C(N)C=C4)=NC=C3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DMX-129 Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMX-1291623123-95-4DMX129DMX 129IKKIκB kinaseI kappa B kinaseΙΚΚεTBK-1Inhibitorinhibitorinhibit

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HY-148206
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