1. Cell Cycle/DNA Damage Anti-infection
  2. DNA/RNA Synthesis Bacterial
  3. DNA Gyrase-IN-8

DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. DNA Gyrase-IN-8 shows antimicrobial activity.

For research use only. We do not sell to patients.

DNA Gyrase-IN-8 Chemical Structure

DNA Gyrase-IN-8 Chemical Structure

CAS No. : 2925308-76-3

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Description

DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. DNA Gyrase-IN-8 shows antimicrobial activity[1].

IC50 & Target

IC50: 8.45 µM (DNA gyrase)[1]

In Vitro

DNA Gyrase-IN-8 (compound 10) shows antimicrobial activity with MIC values of 191.36, 191.36 µM for S. aureus (ATCC 6538-P), C. albicans (ATTC 10231), respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

408.25

Formula

C19H14BrN5O

CAS No.
SMILES

N=C1CC(N)=NN1C(C2=C(C=CC=C3)C3=NC(C4=CC=C(Br)C=C4)=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DNA Gyrase-IN-8
Cat. No.:
HY-149294
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