2. Epigenetics
  3. DNA Methyltransferase
  4. DNMT1-IN-4

DNMT1-IN-4 is a potent non-nucleoside DNA methyltransferase 1 (DNMT1) inhibitor with an IC50 value of 2.5 µM and selectivity towards other AdoMet-dependent protein methyltransferases. DNMT1-IN-4 significantly inhibits cancer cell proliferation.

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DNMT1-IN-4 Chemical Structure

DNMT1-IN-4 Chemical Structure

CAS No. : 889797-65-3

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DNMT1-IN-4 Related Antibodies

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Description

DNMT1-IN-4 is a potent non-nucleoside DNA methyltransferase 1 (DNMT1) inhibitor with an IC50 value of 2.5 µM and selectivity towards other AdoMet-dependent protein methyltransferases. DNMT1-IN-4 significantly inhibits cancer cell proliferation[1].

Molecular Weight

452.38

Formula

C25H23Cl2N3O
CAS No.
SMILES

OC(CNCCC1=CNC2=C1C=CC=C2)CN3C4=C(C=C(C=C4)Cl)C5=C3C=CC(Cl)=C5
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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DNMT1-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNMT1-IN-4889797-65-3DNA MethyltransferaseDNMTsDNA MTasesDNMT1methyltransferasescancer cellInhibitorinhibitorinhibit

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