2. Epigenetics
  3. DNA Methyltransferase
  4. DNMT2-IN-1

DNMT2-IN-1 (compound 80) is a potent and selective DNMT2 (DNA methyltransferase 2) inhibitor with an IC50 value of 1.2 μM, and has the potential for mental and metabolic disorders or cancer research.

For research use only. We do not sell to patients.

DNMT2-IN-1 Chemical Structure

DNMT2-IN-1 Chemical Structure

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DNMT2-IN-1 Related Antibodies

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Description

DNMT2-IN-1 (compound 80) is a potent and selective DNMT2 (DNA methyltransferase 2) inhibitor with an IC50 value of 1.2 μM, and has the potential for mental and metabolic disorders or cancer research[1].

IC50 & Target

DNA methyltransferase 2 (DNMT2) [1] IC50:1.2 μM (DNA methyltransferase 2,DNMT2)[1]
In Vitro

DNMT2-IN-1 (compound 80) (100 μM) inhibits hDNMT2 with inhibitory rate of 98.7%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DNMT2-IN-1 Related Antibodies
Molecular Weight

803.45

Formula

C20H23BrN8O9S.3/2C2HF3O2
SMILES

N[C@H](C(O)=O)CCN(S(=O)(C1=CC([N+]([O-])=O)=C(Br)C=C1)=O)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(N=C3)C(N)=NC=N4)O)O.O=C(O)C(F)(F)F.[3/2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DNMT2-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNMT2-IN-1DNA MethyltransferaseDNMTsDNA MTasesDNMT2Inhibitorinhibitorinhibit

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DNMT2-IN-1
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HY-154867
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