2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Potassium Channel Endogenous Metabolite
  4. Docosahexaenoyl glycine

Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation.

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Docosahexaenoyl glycine Chemical Structure

Docosahexaenoyl glycine Chemical Structure

CAS No. : 132850-40-9

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Based on 1 publication(s) in Google Scholar

Docosahexaenoyl glycine Related Antibodies

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Description

Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation[1].

IC50 & Target

IC50: IKs?Channel[1]
Cellular Effect
Cell Line Type Value Description References
RBL-2H3 IC50
24 μM
Compound: 32
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
[PMID: 31618024]
Sf9 IC50
8.6 μM
Compound: 32
Inhibition of human FAAH expressed in baculovirus infected Sf9 cells using N-(6-methoxypyridin-3-yl)octanamide as substrate measured for 15 mins by fluorescence based assay
Inhibition of human FAAH expressed in baculovirus infected Sf9 cells using N-(6-methoxypyridin-3-yl)octanamide as substrate measured for 15 mins by fluorescence based assay
[PMID: 31618024]
Molecular Weight

385.54

Formula

C24H35NO3
CAS No.
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Docosahexaenoyl glycine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Docosahexaenoyl glycine132850-40-9Potassium ChannelEndogenous MetaboliteKcsAGuinea pig heartIKs channelKCNQ1Kv7.1Long QT SyndromePUFAInhibitorinhibitorinhibit

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