2. GPCR/G Protein Neuronal Signaling Apoptosis NF-κB Stem Cell/Wnt MAPK/ERK Pathway
  3. Opioid Receptor TNF Receptor NF-κB ERK
  4. DOR agonist 2

DOR agonist 2 (Compound 3) is a Delta Opioid Receptor agonist. DOR agonist 2 can inhibit the expression of TNF-α, prevent NF-κB transport to the nucleus, and activate the G protein-mediated ERK1/2 pathway. DOR agonist 2 can be used in the study of neurodegenerative diseases.

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DOR agonist 2 Chemical Structure

DOR agonist 2 Chemical Structure

CAS No. : 1212540-02-7

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DOR agonist 2 Related Antibodies

Top Publications Citing Use of Products

View All Opioid Receptor Isoform Specific Products:

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

View All TNF Receptor Isoform Specific Products:

View All Isoforms
TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

View All ERK Isoform Specific Products:

View All Isoforms
ERK ERK1 ERK2 ERK5 ERK8

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Description

DOR agonist 2 (Compound 3) is a Delta Opioid Receptor agonist. DOR agonist 2 can inhibit the expression of TNF-α, prevent NF-κB transport to the nucleus, and activate the G protein-mediated ERK1/2 pathway. DOR agonist 2 can be used in the study of neurodegenerative diseases[1].

Molecular Weight

450.53

Formula

C29H26N2O3
CAS No.
SMILES

[H][C@]12C(N(C[C@](C2)([H])CN(C(COC3=CC=CC=C3)=O)C1)C(C=C4)=O)=C4C5=CC6=C(C=C5)C=CC=C6
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Room temperature in continental US; may vary elsewhere.
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DOR agonist 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOR agonist 21212540-02-7DOR agonist2DOR agonist-2Opioid ReceptorTNF ReceptorNF-κBERKTumor Necrosis Factor ReceptorTNFRNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesDORAgonistanti-inflammatoryInhibitorinhibitorinhibit

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