Doxorubicinone (Synonyms: Adriamycin aglycone; Adriamycinone)

Cat. No.: HY-121309: FAQs
Data Sheet Handling Instructions

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Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively.

For research use only. We do not sell to patients.

Doxorubicinone Chemical Structure

CAS No. : 24385-10-2

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500 μg	USD 158	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of Doxorubicinone:

Doxorubicinone-d₃ Get quote
Doxorubicinone (Standard) Get quote

2 Publications Citing Use of MCE Doxorubicinone

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Description	Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin^[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively.
Molecular Weight	414.36
Formula	C₂₁H₁₈O₉
CAS No.	24385-10-2
SMILES	OC1=C(C2=C(C(C3=O)=C1C(C4=CC=CC(OC)=C34)=O)O)C[C@](O)(C[C@@H]2O)C(CO)=O
Structure Classification	Quinones Anthraquinones
Initial Source	Endogenous metabolite
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96. [Content Brief]

Doxorubicinone Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Doxorubicinone24385-10-2Adriamycin aglycone AdriamycinoneEndogenous MetaboliteInhibitorinhibitorinhibit

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Doxorubicinone (Synonyms: Adriamycin aglycone; Adriamycinone)

Other Forms of Doxorubicinone:

Doxorubicinone Related Antibodies

2 Publications Citing Use of MCE Doxorubicinone

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review